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Inhibition of Rho-Kinase Downregulates Th17 Cells and Ameliorates Hepatic Fibrosis by Schistosoma japonicum Infection

Background: Schistosomiasis is an immunopathogenic disease in which Th17 cells play vital roles. Hepatic granuloma formation and subsequent fibrosis are its main pathologic manifestations and the leading causes of hepatic cirrhosis, and effective therapeutic interventions are lacking. In this study,...

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Bibliografiske detaljer
Udgivet i:Cells
Main Authors: Zhou, Wei, Yang, Yingying, Mei, Congjin, Dong, Panpan, Mu, Shasha, Wu, Hongchu, Zhou, Yonghua, Zheng, Yi, Guo, Fukun, Yang, Jun-Qi
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829618/
https://ncbi.nlm.nih.gov/pubmed/31623153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8101262
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