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Increased Regeneration Following Stress-Induced Lung Injury in Bleomycin-Treated Chimeric Mice with CD44 Knockout Mesenchymal Cells

CD44, an adhesion-molecule promoting cell-migration, is shown here to increase in stress conditions following bleomycin-induced apoptosis in alveolar epithelial cells (AECs), a main target of lung injury. In vivo, it inhibits tissue regeneration and leads to fibrosis. We show that some AECs survive...

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Bibliografski detalji
Izdano u:Cells
Glavni autori: Petukhov, Dmytro, Richter-Dayan, Mark, Fridlender, Zvi, Breuer, Raphael, Wallach-Dayan, Shulamit B.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829612/
https://ncbi.nlm.nih.gov/pubmed/31591327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8101211
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