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Activation of TRPA1 by volatile organic chemicals leading to sensory irritation

Many volatile organic chemicals (VOCs) have not been tested for sensory pulmonary irritation. Development of in vitro non-animal sensory irritation assay suitable for large number of chemicals is needed to replace the mouse assay. An adverse outcome pathway (AOP) was developed to provide a clear des...

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Detalhes bibliográficos
Publicado no:ALTEX
Main Authors: Martinez, Jeanelle M., Eling, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829608/
https://ncbi.nlm.nih.gov/pubmed/31026039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14573/altex.1811012
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