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Low temperature traps myosin motors of mammalian muscle in a refractory state that prevents activation
Myosin motors in the thick filament of resting striated (skeletal and cardiac) muscle are trapped in an OFF state, in which the motors are packed in helical tracks on the filament surface, inhibiting their interactions with actin and utilization of ATP. To investigate the structural changes induced...
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| 出版年: | J Gen Physiol |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Rockefeller University Press
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6829559/ https://ncbi.nlm.nih.gov/pubmed/31554652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201912424 |
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