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The Role of Immune Checkpoint Receptors in Regulating Immune Reactivity in Lupus
Immune checkpoint receptors with co-stimulatory and co-inhibitory signals are important modulators for the immune system. However, unrestricted co-stimulation and/or inadequate co-inhibition may cause breakdown of self-tolerance, leading to autoimmunity. Systemic lupus erythematosus (SLE) is a compl...
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| Publié dans: | Cells |
|---|---|
| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6829486/ https://ncbi.nlm.nih.gov/pubmed/31597242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8101213 |
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