The Role of Immune Checkpoint Receptors in Regulating Immune Reactivity in Lupus

Immune checkpoint receptors with co-stimulatory and co-inhibitory signals are important modulators for the immune system. However, unrestricted co-stimulation and/or inadequate co-inhibition may cause breakdown of self-tolerance, leading to autoimmunity. Systemic lupus erythematosus (SLE) is a compl...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cells
Hauptverfasser: Lu, Kun-Lin, Wu, Ming-Ying, Wang, Chi-Hui, Wang, Chuang-Wei, Hung, Shuen-Iu, Chung, Wen-Hung, Chen, Chun-Bing
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829486/
https://ncbi.nlm.nih.gov/pubmed/31597242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8101213
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