Leptin Promotes Expression of EMT-Related Transcription Factors and Invasion in a Src and FAK-Dependent Pathway in MCF10A Mammary Epithelial Cells

Leptin is one of the main adipokines secreted in breast tissue. Leptin promotes epithelial–mesenchymal transition (EMT), cell migration and invasion in epithelial breast cells, leading to tumor progression. Although, the molecular mechanisms that underlie these events are not fully understood, the a...

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Xehetasun bibliografikoak
Argitaratua izan da:Cells
Egile Nagusiak: Olea-Flores, Monserrat, Zuñiga-Eulogio, Miriam, Tacuba-Saavedra, Arvey, Bueno-Salgado, Magdalena, Sánchez-Carvajal, Andrea, Vargas-Santiago, Yovani, Mendoza-Catalán, Miguel A., Pérez Salazar, Eduardo, García-Hernández, Alejandra, Padilla-Benavides, Teresita, Navarro-Tito, Napoleón
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829404/
https://ncbi.nlm.nih.gov/pubmed/31554180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8101133
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