Combination of SAXS and Protein Painting Discloses the Three-Dimensional Organization of the Bacterial Cysteine Synthase Complex, a Potential Target for Enhancers of Antibiotic Action

The formation of multienzymatic complexes allows for the fine tuning of many aspects of enzymatic functions, such as efficiency, localization, stability, and moonlighting. Here, we investigated, in solution, the structure of bacterial cysteine synthase (CS) complex. CS is formed by serine acetyltran...

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Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Rosa, Brenda, Marchetti, Marialaura, Paredi, Gianluca, Amenitsch, Heinz, Franko, Nina, Benoni, Roberto, Giabbai, Barbara, De Marino, Maria Giovanna, Mozzarelli, Andrea, Ronda, Luca, Storici, Paola, Campanini, Barbara, Bettati, Stefano
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829319/
https://ncbi.nlm.nih.gov/pubmed/31640223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20205219
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