Combination of SAXS and Protein Painting Discloses the Three-Dimensional Organization of the Bacterial Cysteine Synthase Complex, a Potential Target for Enhancers of Antibiotic Action

The formation of multienzymatic complexes allows for the fine tuning of many aspects of enzymatic functions, such as efficiency, localization, stability, and moonlighting. Here, we investigated, in solution, the structure of bacterial cysteine synthase (CS) complex. CS is formed by serine acetyltran...

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Pubblicato in:Int J Mol Sci
Autori principali: Rosa, Brenda, Marchetti, Marialaura, Paredi, Gianluca, Amenitsch, Heinz, Franko, Nina, Benoni, Roberto, Giabbai, Barbara, De Marino, Maria Giovanna, Mozzarelli, Andrea, Ronda, Luca, Storici, Paola, Campanini, Barbara, Bettati, Stefano
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829319/
https://ncbi.nlm.nih.gov/pubmed/31640223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20205219
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