Glomerular Complement Factor H–Related Protein 5 (FHR5) Is Highly Prevalent in C3 Glomerulopathy and Associated With Renal Impairment

INTRODUCTION: Therapeutic agents that target complement are increasingly available for glomerular diseases. However, the mechanisms linking glomerular complement deposition with inflammation and damage are incompletely understood. Complement factor H–related protein 5 (FHR5) interacts with complemen...

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Detalhes bibliográficos
Publicado no:Kidney Int Rep
Main Authors: Medjeral-Thomas, Nicholas R., Moffitt, Hilary, Lomax-Browne, Hannah J., Constantinou, Nicholas, Cairns, Tom, Cook, H. Terence, Pickering, Matthew C.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Clinical Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829196/
https://ncbi.nlm.nih.gov/pubmed/31701048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ekir.2019.06.008
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