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Chromosome Preference During Homologous Recombination Repair of DNA Double-Strand Breaks in Drosophila melanogaster

DNA double-strand breaks (DSBs) are especially toxic DNA lesions that, if left unrepaired, can lead to wide-ranging genomic instability. Of the pathways available to repair DSBs, the most accurate is homologous recombination (HR), where a homologous sequence is used as a donor template to restore ge...

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Bibliografiske detaljer
Udgivet i:G3 (Bethesda)
Main Authors: Fernandez, Joel, Bloomer, Hanan, Kellam, Natalia, LaRocque, Jeannine R.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829126/
https://ncbi.nlm.nih.gov/pubmed/31519746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.119.400607
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