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Evaluation of antibodies for western blot analysis of frataxin protein isoforms
Frataxin is the protein that is down-regulated in Friedreich ataxia (FRDA), an autosomal recessive genetic disease caused by an intronic GAA repeat expansion in intron-1 of the FXN gene. The GAA repeats result in epigenetic silencing of the FXN gene and reduced expression of the cytosolic full-lengt...
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| Publicado no: | J Immunol Methods |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6829029/ https://ncbi.nlm.nih.gov/pubmed/31279523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2019.07.001 |
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