Increased Tim-3 expression alleviates liver injury by regulating macrophage activation in MCD-induced NASH mice

As an immune checkpoint, Tim-3 plays roles in the regulation of both adaptive and innate immune cells including macrophages and is greatly involved in chronic liver diseases. However, the precise roles of Tim-3 in nonalcoholic steatohepatitis (NASH) remain unstated. In the current study, we analyzed...

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Bibliografske podrobnosti
izdano v:Cell Mol Immunol
Main Authors: Du, Xianhong, Wu, Zhuanchang, Xu, Yong, Liu, Yuan, Liu, Wen, Wang, Tixiao, Li, Chunyang, Zhang, Cuijuan, Yi, Fan, Gao, Lifen, Liang, Xiaohong, Ma, Chunhong
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6828758/
https://ncbi.nlm.nih.gov/pubmed/29735977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-018-0032-0
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