Resveratrol Reverses Retinoic Acid Resistance of Anaplastic Thyroid Cancer Cells via Demethylating CRABP2 Gene

Background: Cellular retinoic acid binding protein 2 (CRABP2) mediates retinoic acid/RA anti-cancer pathways. Resveratrol effectively reverses RA tolerance and upregulates CRABP2 expression of anaplastic thyroid cancer cell line THJ-11T. As DNA methylation is responsible for CRABP2 silencing, the CR...

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Vydáno v:Front Endocrinol (Lausanne)
Hlavní autoři: Liu, Xin, Li, Hong, Wu, Mo-Li, Wu, Jiao, Sun, Yuan, Zhang, Kai-Li, Liu, Jia
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Endocrinology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6828648/
https://ncbi.nlm.nih.gov/pubmed/31736873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00734
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