Current Anti-HPA-1a Standard Antibodies React with the β3 Integrin Subunit but not with αIIbβ3 and αvβ3 Complexes

BACKGROUND: Fetal/neonatal alloimmune thrombocytopenia (FNAIT) results from maternal alloantibodies (abs) reacting with fetal platelets expressing paternal human platelet antigens (HPAs), mostly HPA-1a. Anti-HPA-1a abs, are the most frequent cause of severe thrombocytopenia and intracranial hemorrha...

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Publicado en:Thromb Haemost
Autores principales: Bayat, Behnaz, Traum, Annalena, Berghöfer, Heike, Werth, Silke, Zhu, Jieging, Bein, Gregor, Sachs, Ulrich J., Santoso, Sentot
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6827430/
https://ncbi.nlm.nih.gov/pubmed/31587244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0039-1696716
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