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Comparison of the Full Distribution of Fitness Effects of New Amino Acid Mutations Across Great Apes

The distribution of fitness effects (DFE) is central to many questions in evolutionary biology. However, little is known about the differences in DFE between closely related species. We use >9000 coding genes orthologous one-to-one across great apes, gibbons, and macaques to assess the stability...

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Bibliografiske detaljer
Udgivet i:Genetics
Main Authors: Castellano, David, Macià, Moisès Coll, Tataru, Paula, Bataillon, Thomas, Munch, Kasper
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6827385/
https://ncbi.nlm.nih.gov/pubmed/31488516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302494
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