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Proteomic mapping by rapamycin-dependent targeting of APEX2 identifies binding partners of VAPB at the inner nuclear membrane

Vesicle-associated membrane protein–associated protein B (VAPB) is a tail-anchored protein that is present at several contact sites of the endoplasmic reticulum (ER). We now show by immunoelectron microscopy that VAPB also localizes to the inner nuclear membrane (INM). Using a modified enhanced asco...

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Pubblicato in:J Biol Chem
Autori principali: James, Christina, Müller, Marret, Goldberg, Martin W., Lenz, Christof, Urlaub, Henning, Kehlenbach, Ralph H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6827323/
https://ncbi.nlm.nih.gov/pubmed/31519755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007283
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