Proteomic mapping by rapamycin-dependent targeting of APEX2 identifies binding partners of VAPB at the inner nuclear membrane

Vesicle-associated membrane protein–associated protein B (VAPB) is a tail-anchored protein that is present at several contact sites of the endoplasmic reticulum (ER). We now show by immunoelectron microscopy that VAPB also localizes to the inner nuclear membrane (INM). Using a modified enhanced asco...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: James, Christina, Müller, Marret, Goldberg, Martin W., Lenz, Christof, Urlaub, Henning, Kehlenbach, Ralph H.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2019
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6827323/
https://ncbi.nlm.nih.gov/pubmed/31519755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007283
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