The human cytomegalovirus-encoded G protein–coupled receptor UL33 exhibits oncomodulatory properties

Herpesviruses can rewire cellular signaling in host cells by expressing viral G protein–coupled receptors (GPCRs). These viral receptors exhibit homology to human chemokine receptors, but some display constitutive activity and promiscuous G protein coupling. Human cytomegalovirus (HCMV) has been det...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: van Senten, Jeffrey R., Bebelman, Maarten P., Fan, Tian Shu, Heukers, Raimond, Bergkamp, Nick D., van Gasselt, Puck, Langemeijer, Ellen V., Slinger, Erik, Lagerweij, Tonny, Rahbar, Afsar, Stigter-van Walsum, Marijke, Maussang, David, Leurs, Rob, Musters, René J. P., van Dongen, Guus A. M. S., Söderberg-Nauclér, Cecilia, Würdinger, Thomas, Siderius, Marco, Smit, Martine J.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2019
Sujets:
Molecular Bases of Disease
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6827316/
https://ncbi.nlm.nih.gov/pubmed/31519750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007796
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