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N-Glycosylation of the voltage-gated sodium channel β2 subunit is required for efficient trafficking of Na(V)1.5/β2 to the plasma membrane

The voltage-gated sodium channel is critical for cardiomyocyte function and consists of a protein complex comprising a pore-forming α subunit and two associated β subunits. It has been shown previously that the associated β2 subunits promote cell surface expression of the α subunit. The major α isof...

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Publicat a:J Biol Chem
Autors principals: Cortada, Eric, Brugada, Ramon, Verges, Marcel
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6827310/
https://ncbi.nlm.nih.gov/pubmed/31511323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007903
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