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Growth hormone induces Notch1 signaling in podocytes and contributes to proteinuria in diabetic nephropathy
Growth hormone (GH) plays a significant role in normal renal function and overactive GH signaling has been implicated in proteinuria in diabetes and acromegaly. Previous results have shown that the glomerular podocytes, which play an essential role in renal filtration, express the GH receptor, sugge...
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| Publicado no: | J Biol Chem |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6827306/ https://ncbi.nlm.nih.gov/pubmed/31511328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008966 |
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