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MaveDB: an open-source platform to distribute and interpret data from multiplexed assays of variant effect

Multiplex assays of variant effect (MAVEs), such as deep mutational scans and massively parallel reporter assays, test thousands of sequence variants in a single experiment. Despite the importance of MAVE data for basic and clinical research, there is no standard resource for their discovery and dis...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Esposito, Daniel, Weile, Jochen, Shendure, Jay, Starita, Lea M., Papenfuss, Anthony T., Roth, Frederick P., Fowler, Douglas M., Rubin, Alan F.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6827219/
https://ncbi.nlm.nih.gov/pubmed/31679514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1845-6
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