STAT3 Activity Promotes Programmed-Death Ligand 1 Expression and Suppresses Immune Responses in Breast Cancer

Signal transducer and activator of transcription 3 (STAT3) is an oncogene and multifaceted transcription factor involved in multiple cellular functions. Its role in modifying anti-tumor immunity has been recently recognized. In this study, the biologic effects of STAT3 on immune checkpoint expressio...

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Détails bibliographiques
Publié dans:Cancers (Basel)
Auteurs principaux: Zerdes, Ioannis, Wallerius, Majken, Sifakis, Emmanouil G., Wallmann, Tatjana, Betts, Stina, Bartish, Margarita, Tsesmetzis, Nikolaos, Tobin, Nicholas P., Coucoravas, Christos, Bergh, Jonas, Rassidakis, George Z., Rolny, Charlotte, Foukakis, Theodoros
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6827034/
https://ncbi.nlm.nih.gov/pubmed/31581535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11101479
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