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Genetic, transcriptional and post-translational regulation of the programmed death protein ligand 1 in cancer: biology and clinical correlations

The programmed death protein 1 (PD-1) and its ligand (PD-L1) represent a well-characterized immune checkpoint in cancer, effectively targeted by monoclonal antibodies that are approved for routine clinical use. The regulation of PD-L1 expression is complex, varies between different tumor types and o...

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書目詳細資料
發表在:Oncogene
Main Authors: Zerdes, Ioannis, Matikas, Alexios, Bergh, Jonas, Rassidakis, George Z., Foukakis, Theodoros
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107481/
https://ncbi.nlm.nih.gov/pubmed/29765155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0303-3
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