Mutational Landscape of the BAP1 Locus Reveals an Intrinsic Control to Regulate the miRNA Network and the Binding of Protein Complexes in Uveal Melanoma

The BAP1 (BRCA1-associated protein 1) gene is associated with a variety of human cancers. With its gene product being a nuclear ubiquitin carboxy-terminal hydrolase with deubiquitinase activity, BAP1 acts as a tumor suppressor gene with potential pleiotropic effects in multiple tumor types. Herein,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cancers (Basel)
मुख्य लेखकों: Sharma, Amit, Biswas, Arijit, Liu, Hongde, Sen, Sagnik, Paruchuri, Anoosha, Katsonis, Panagiotis, Lichtarge, Olivier, Chand Dakal, Tikam, Maulik, Ujjwal, Gromiha, M. Michael, Bandyopadhyay, Sanghamitra, Ludwig, Michael, Holz, Frank G., Loeffler, Karin U., Herwig-Carl, Martina C.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI 2019
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826957/
https://ncbi.nlm.nih.gov/pubmed/31635116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11101600
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