Spironolactone, a Classic Potassium-Sparing Diuretic, Reduces Survivin Expression and Chemosensitizes Cancer Cells to Non-DNA-Damaging Anticancer Drugs

Spironolactone, a classical diuretic drug, is used to treat tumor-associated complications in cancer patients. Spironolactone was recently reported to exert anti-cancer effects by suppressing DNA damage repair. However, it currently remains unclear whether spironolactone exerts combinational effects...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Sanomachi, Tomomi, Suzuki, Shuhei, Togashi, Keita, Sugai, Asuka, Seino, Shizuka, Okada, Masashi, Yoshioka, Takashi, Kitanaka, Chifumi, Yamamoto, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826935/
https://ncbi.nlm.nih.gov/pubmed/31614999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11101550
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