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Microsatellite Instability: Diagnosis, Heterogeneity, Discordance, and Clinical Impact in Colorectal Cancer

Tumor DNA mismatch repair (MMR) deficiency testing is important to the identification of Lynch syndrome and decision making regarding adjuvant chemotherapy in stage II colorectal cancer (CRC) and has become an indispensable test in metastatic tumors due to the high efficacy of immune checkpoint inhi...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Evrard, Camille, Tachon, Gaëlle, Randrian, Violaine, Karayan-Tapon, Lucie, Tougeron, David
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826728/
https://ncbi.nlm.nih.gov/pubmed/31618962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11101567
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