Discordance between immunochemistry of mismatch repair proteins and molecular testing of microsatellite instability in colorectal cancer

BACKGROUND: DNA mismatch repair system deficiency (dMMR) is found in 15% of colorectal cancers (CRCs). Two methods are used to determine dMMR, immunohistochemistry (IHC) of MMR proteins and molecular testing of microsatellite instability (MSI). Only studies with a low number of patients have reporte...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:ESMO Open
Asıl Yazarlar: Guyot D'Asnières De Salins, A., Tachon, G., Cohen, R., Karayan-Tapon, L., Junca, A., Frouin, E., Godet, J., Evrard, C., Randrian, V., Duval, A., Svrcek, M., Lascols, O., Vignot, S., Coulet, F., André, T., Fléjou, J.-F., Cervera, P., Tougeron, D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2021
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102173/
https://ncbi.nlm.nih.gov/pubmed/33930657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.esmoop.2021.100120
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