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Mesenchymal Cells Support the Oncogenicity and Therapeutic Response of the Hedgehog Pathway in Triple-Negative Breast Cancer

The paracrine interaction between tumor cells and adjacent stroma has been associated with the oncogenic activity of the Hedgehog (Hh) pathway in triple-negative breast tumors. The present study developed a model of paracrine Hh signaling and examined the impact of mesenchymal cell sources and cultu...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Reyes-Ramos, Ana M., Ramos-Cruz, Karla P., Rodríguez-Merced, Nelson J., Martínez-Montemayor, Michelle M., Franqui-Ríos, Nelson D., Ríos-Grant, Jan P., Flores, Andrea, Maldonado-Martínez, Gerónimo, Torres-García, Wandaliz, Domenech, Maribella
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826628/
https://ncbi.nlm.nih.gov/pubmed/31658643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11101522
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