Caricamento...
Heterogeneous beta-catenin activation is sufficient to cause hepatocellular carcinoma in zebrafish
Up to 41% of hepatocellular carcinomas (HCCs) result from activating mutations in the CTNNB1 gene encoding β-catenin. HCC-associated CTNNB1 mutations stabilize the β-catenin protein, leading to nuclear and/or cytoplasmic localization of β-catenin and downstream activation of Wnt target genes. In pat...
Salvato in:
| Pubblicato in: | Biol Open |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Company of Biologists Ltd
2019
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6826293/ https://ncbi.nlm.nih.gov/pubmed/31575545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.047829 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|