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Acid sphingomyelinase regulates the localization and trafficking of palmitoylated proteins
In human, loss of acid sphingomyelinase (ASM/SMPD1) causes Niemann–Pick disease, type A. ASM hydrolyzes sphingomyelins to produce ceramides but protein targets of ASM remain largely unclear. Our mass spectrometry-based proteomic analyses have identified >100 proteins associated with the ASM-depen...
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| Publicado no: | Biol Open |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6826292/ https://ncbi.nlm.nih.gov/pubmed/31142470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.040311 |
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