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Palmitoylation regulates the intracellular trafficking and stability of c-Met

c-Met is a receptor tyrosine kinase whose activity can promote both mitogenic and motogenic phenotypes involved in tissue development and cancer progression. Herein, we report the first evidence that c-Met is palmitoylated and that palmitoylation facilitates its trafficking and stability. Inhibition...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Coleman, David T., Gray, Alana L., Kridel, Steven J., Cardelli, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078042/
https://ncbi.nlm.nih.gov/pubmed/27081699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8706
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