ロード中...
Chromatin‐bound cGAS is an inhibitor of DNA repair and hence accelerates genome destabilization and cell death
DNA repair via homologous recombination (HR) is indispensable for genome integrity and cell survival but if unrestrained can result in undesired chromosomal rearrangements. The regulatory mechanisms of HR are not fully understood. Cyclic GMP‐AMP synthase (cGAS) is best known as a cytosolic innate im...
保存先:
| 出版年: | EMBO J |
|---|---|
| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2019
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6826206/ https://ncbi.nlm.nih.gov/pubmed/31544964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019102718 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|