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Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts
Somatic mutations are critical for cancer development and may play a role in age‐related functional decline. Here, we used deep sequencing to analyze the prevalence of somatic mutations during in vitro cell aging. Primary dermal fibroblasts from healthy subjects of young and advanced age, from Hutch...
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| 出版年: | Aging Cell |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6826141/ https://ncbi.nlm.nih.gov/pubmed/31385397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13010 |
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