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Annexin A5 regulates surface αvβ5 integrin for retinal clearance phagocytosis

Diurnal clearance phagocytosis by the retinal pigment epithelium (RPE) is a conserved efferocytosis process whose binding step is mediated by αvβ5 integrin receptors. Two related annexins, A5 (ANXA5) and A6 (ANXA6), share an αvβ5 integrin-binding motif. Here, we report that ANXA5, but not ANXA6, reg...

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Bibliografiske detaljer
Udgivet i:J Cell Sci
Main Authors: Yu, Chen, Muñoz, Luis E., Mallavarapu, Mallika, Herrmann, Martin, Finnemann, Silvia C.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826004/
https://ncbi.nlm.nih.gov/pubmed/31515275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.232439
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