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Loss of Synchronized Retinal Phagocytosis and Age-related Blindness in Mice Lacking αvβ5 Integrin

Daily phagocytosis by the retinal pigment epithelium (RPE) of spent photoreceptor outer segment fragments is critical for vision. In the retina, early morning circadian photoreceptor rod shedding precedes synchronized uptake of shed photoreceptor particles by RPE cells. In vitro, RPE cells use the i...

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Detalhes bibliográficos
Main Authors: Nandrot, Emeline F., Kim, Yoonhee, Brodie, Scott E., Huang, Xiaozhu, Sheppard, Dean, Finnemann, Silvia C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211990/
https://ncbi.nlm.nih.gov/pubmed/15596525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041447
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