MTDH/AEG-1 downregulation using pristimerin-loaded nanoparticles inhibits Fanconi anemia proteins and increases sensitivity to platinum-based chemotherapy

OBJECTIVE: Platinum compounds have been widely used as a primary treatment for many types of cancer. However, resistance is the major cause of therapeutic failure for patients with metastatic or recurrent disease, thus highlighting the need to identify novel factors driving resistance to Platinum co...

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Detaylı Bibliyografya
Yayımlandı:Gynecol Oncol
Asıl Yazarlar: Bi, Jianling, Areecheewakul, Sudartip, Li, Yujun, Yang, Shujie, Zhang, Yuping, Ebeid, Kareem, Li, Long, Thiel, Kristina W, Zhang, Jun, Dai, Donghai, Salem, Aliasger K., Leslie, Kimberly K., Meng, Xiangbing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825893/
https://ncbi.nlm.nih.gov/pubmed/31477281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2019.08.014
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