MTDH/AEG-1 downregulation using pristimerin-loaded nanoparticles inhibits Fanconi anemia proteins and increases sensitivity to platinum-based chemotherapy

OBJECTIVE: Platinum compounds have been widely used as a primary treatment for many types of cancer. However, resistance is the major cause of therapeutic failure for patients with metastatic or recurrent disease, thus highlighting the need to identify novel factors driving resistance to Platinum co...

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Publicado no:Gynecol Oncol
Main Authors: Bi, Jianling, Areecheewakul, Sudartip, Li, Yujun, Yang, Shujie, Zhang, Yuping, Ebeid, Kareem, Li, Long, Thiel, Kristina W, Zhang, Jun, Dai, Donghai, Salem, Aliasger K., Leslie, Kimberly K., Meng, Xiangbing
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825893/
https://ncbi.nlm.nih.gov/pubmed/31477281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2019.08.014
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