Antibodies to a Conserved Influenza Head-interface Epitope Protect by an IgG Subtype Dependent Mechanism

Vaccines to generate durable humoral immunity against antigenically evolving pathogens such as influenza virus must elicit antibodies that recognize conserved epitopes. Analysis of single memory B cells from immunized human donors has led us to characterize a previously unrecognized epitope of influ...

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Bibliographic Details
Published in:Cell
Main Authors: Watanabe, Akiko, McCarthy, Kevin R., Kuraoka, Masayuki, Schmidt, Aaron G., Adachi, Yu, Onodera, Taishi, Tonouchi, Keisuke, Caradonna, Timothy M., Bajic, Goran, Song, Shengli, McGee, Charles E., Sempowski, Gregory D., Feng, Feng, Urick, Patricia, Kepler, Thomas B., Takahashi, Yoshimasa, Harrison, Stephen C., Kelsoe, Garnett
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825805/
https://ncbi.nlm.nih.gov/pubmed/31100267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.03.048
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