Antibodies to a Conserved Influenza Head-interface Epitope Protect by an IgG Subtype Dependent Mechanism

Vaccines to generate durable humoral immunity against antigenically evolving pathogens such as influenza virus must elicit antibodies that recognize conserved epitopes. Analysis of single memory B cells from immunized human donors has led us to characterize a previously unrecognized epitope of influ...

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Veröffentlicht in:Cell
Hauptverfasser: Watanabe, Akiko, McCarthy, Kevin R., Kuraoka, Masayuki, Schmidt, Aaron G., Adachi, Yu, Onodera, Taishi, Tonouchi, Keisuke, Caradonna, Timothy M., Bajic, Goran, Song, Shengli, McGee, Charles E., Sempowski, Gregory D., Feng, Feng, Urick, Patricia, Kepler, Thomas B., Takahashi, Yoshimasa, Harrison, Stephen C., Kelsoe, Garnett
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825805/
https://ncbi.nlm.nih.gov/pubmed/31100267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.03.048
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