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STING signaling in melanoma cells shapes antigenicity and can promote antitumor T-cell activity

STING (stimulator of IFN genes) signaling is an innate immune pathway for induction of a spontaneous antitumor T cell response against certain immunogenic tumors. Although antigen presenting cells are known to be involved in this process, insight into the participation of tumor cell-intrinsic STING...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Falahat, Rana, Perez-Villarroel, Patricio, Mailloux, Adam W., Zhu, Genyuan, Pilon-Thomas, Shari, Barber, Glen N., Mulé, James J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825582/
https://ncbi.nlm.nih.gov/pubmed/31462408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-19-0229
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