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A Phase II Trial of Hu14.18K322A in Combination with Induction Chemotherapy in Children with Newly Diagnosed High-Risk Neuroblastoma.

PURPOSE: Evaluate whether combining a humanized anti-disialoganglioside monoclonal antibody (hu14.18K322A) with induction chemotherapy improves early responses and outcomes in children with newly diagnosed high-risk neuroblastoma. PATIENTS AND METHODS: We conducted a prospective nonrandomized, singl...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Furman, Wayne L., Federico, Sara M., McCarville, Mary Beth, Shulkin, Barry L., Davidoff, Andrew M., Krasin, Matthew J., Sahr, Natasha, Sykes, April, Wu, Jianrong, Brennan, Rachel C., Bishop, Michael William, Helmig, Sara, Stewart, Elizabeth, Navid, Fariba, Triplett, Brandon, Santana, Victor M., Bahrami, Armita, Anthony, Gwendolyn, Yu, Alice L., Hank, Jacquelyn, Gillies, Stephen D., Sondel, Paul M., Leung, Wing H., Pappo, Alberto S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825564/
https://ncbi.nlm.nih.gov/pubmed/31601569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-1452
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