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Enhancement of the anti-melanoma response of Hu14.18K322A by αCD40 + CpG

Targeted monoclonal antibodies (mAb) can be used therapeutically for tumors with identifiable antigens such as disialoganglioside GD2, expressed on neuroblastoma and melanoma tumors. Anti-GD2 mAbs (αGD2) can provide clinical benefit in patients with neuroblastoma. An important mechanism of mAb thera...

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Bibliographic Details
Main Authors: Alderson, Kory L., Luangrath, Mitchell, Elsenheimer, Megan M., Gillies, Stephen D., Navid, Fariba, Rakhmilevich, Alexander L., Sondel, Paul M.
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578100/
https://ncbi.nlm.nih.gov/pubmed/23151945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-012-1372-8
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