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Antitumor effects of anti-CD40/CpG immunotherapy combined with gemcitabine or 5-fluorouracil chemotherapy in the B16 melanoma model

Our previous studies demonstrated that anti-CD40 mAb (anti-CD40) can synergize with CpG oligodeoxynucleotides (CpG) to mediate antitumor effects by activating myeloid cells, such as macrophages in tumor-bearing mice. Separate teams have shown that chemotherapy with gemcitabine (GEM) or 5-fluorouraci...

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Detalhes bibliográficos
Main Authors: Qu, Xiaoyi, Felder, Mildred A.R., Horta, Zulmarie Perez, Sondel, Paul M., Rakhmilevich, Alexander L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873769/
https://ncbi.nlm.nih.gov/pubmed/24201083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2013.10.019
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