Leukotriene synthesis is critical for medulloblastoma progression

PURPOSE: Here, we examined the role of leukotriene, well-known inflammatory mediators, in the tumorigenesis of hedgehog pathway-associated medulloblastoma (MB), and tested the efficacies of antagonists of leukotriene biosynthesis in MB treatment. EXPERIMENTAL DESIGN: We examined the leukotriene leve...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Du, Fang, Yuelling, Larra, Lee, Eric H., Wang, Yuan, Liao, Shengyou, Cheng, Yan, Zhang, Li, Zheng, Chaonan, Peri, Suraj, Cai, Kathy Q., Ng, Jessica M. Y., Curran, Tom, Li, Peng, Yang, Zeng-jie
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825543/
https://ncbi.nlm.nih.gov/pubmed/31300449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-3549
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