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The EGFR Exon 19 Mutant L747-A750>P Exhibits Distinct Sensitivity to Tyrosine Kinase Inhibitors in Lung Adenocarcinoma
PURPOSE: EGFR exon 19 deletion (Ex19Del) mutations account for ~60% of lung cancer-associated EGFR mutations and include a heterogeneous group of mutations. Although they are associated with benefit from tyrosine kinase inhibitors (TKIs), the relative inhibitor sensitivity of individual Ex19Del muta...
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| Опубликовано в: : | Clin Cancer Res |
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| Главные авторы: | , , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6825535/ https://ncbi.nlm.nih.gov/pubmed/31182434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-0780 |
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