Optimized filopodia formation requires myosin tail domain cooperation

Filopodia are actin-filled protrusions employed by cells to interact with their environment. Filopodia formation in Amoebozoa and Metazoa requires the phylogenetically diverse MyTH4-FERM (MF) myosins DdMyo7 and Myo10, respectively. While Myo10 is known to form antiparallel dimers, DdMyo7 lacks a coi...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Arthur, Ashley L., Songster, Livia D., Sirkia, Helena, Bhattacharya, Akash, Kikuti, Carlos, Borrega, Fernanda Pires, Houdusse, Anne, Titus, Margaret A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825318/
https://ncbi.nlm.nih.gov/pubmed/31611382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901527116
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