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Germline variants associated with leukocyte genes predict tumor recurrence in breast cancer patients

Germline variants such as BRCA1/2 play an important role in tumorigenesis and clinical outcomes of cancer patients. However, only a small fraction (i.e., 5–10%) of inherited variants has been associated with clinical outcomes (e.g., BRCA1/2, APC, TP53, PTEN and so on). The challenge remains in using...

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Bibliografski detalji
Izdano u:NPJ Precis Oncol
Glavni autori: Milanese, Jean-Sébastien, Tibiche, Chabane, Zou, Jinfeng, Meng, Zhigang, Nantel, Andre, Drouin, Simon, Marcotte, Richard, Wang, Edwin
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825127/
https://ncbi.nlm.nih.gov/pubmed/31701019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-019-0100-7
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