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Functional Characterization of Pharmcogenetic Variants of Human Cytochrome P450 2C9 in Korean Populations
Human cytochrome P450 2C9 is a highly polymorphic enzyme that is required for drug and xenobiotic metabolism. Here, we studied eleven P450 2C9 genetic variants—including three novel variants F69S, L310V, and Q324X—that were clinically identified in Korean patients. P450 2C9 variant enzymes were expr...
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| Publicado no: | Biomol Ther (Seoul) |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Korean Society of Applied Pharmacology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6824622/ https://ncbi.nlm.nih.gov/pubmed/31484472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2019.112 |
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