Histone demethylase LSD1 deficiency and biological sex: impact on blood pressure and aldosterone production

Human risk allele carriers of lysine-specific demethylase 1 (LSD1) and LSD1-deficient mice have salt-sensitive hypertension for unclear reasons. We hypothesized that LSD1 deficiency causes dysregulation of aldosterone’s response to salt intake resulting in increased cardiovascular risk factors (bloo...

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Bibliografiske detaljer
Udgivet i:J Endocrinol
Main Authors: Huang, Yuefei, Ting, Pei Yee, Yao, Tham M, Homma, Tsuyoshi, Brooks, Danielle, Rangel, Isis Katayama, Adler, Gail K, Romero, Jose R, Williams, Jonathan S, Pojoga, Luminita H, Williams, Gordon H
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824586/
https://ncbi.nlm.nih.gov/pubmed/30400034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-18-0247
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